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What are the Benefits?

There are over 70 diseases that have been treated with adult stem cells including tissue and blood cancer, sickle cell and aplastic anemias, autoimmune diseases, neurological disorders, arthritis, etc. Results from both animal studies and early human clinical trials indicate that they have significant capabilities for growth, repair, and regeneration of damaged cells and tissues in the body. Think of them as a built-in maintenance crew that only needs activation and stimulation to identify and repair damage.¹⁵ Tissue therapies include the regeneration of bone, cartilage and organs - most notably the heart and breast.

Over 6,000 patients were treated in the U.S. alone with stem cells in 2006. The potential of adult stem cells to impact medicine in this respect is enormous.¹⁶

	Malignancies Acute lymphocytic leukemia (ALL) Acute myelogenous leukemia (AML) Chronic myelocytic leukemia (CML) Myelodysplastic syndrome (MDS)

	Solid Tumors Liposarcoma Neuroblastoma Non-Hodgkin’s lymphoma Yolk sac sarcoma

	Hemoglobinopathies & Various Blood Disorders Amegakaryocytic thrombocytopenia (AMT) Aplastic anemia Blackfan-Diamond anemia Congenital cytopenia Fanconi’s anemia (genetic) Kostmann’s syndrome (genetic) Sickle cell anemia Thalassemia

Inborn Errors of Metabolism

Adrenoleukodystrophy
Bare-lymphocyte syndrome
Dyskeratosis congenita
Familial erythrophagocytic
lymphohistiocytosis
Gaucher disease
Gunter disease
Hunter syndrome
Hurler syndrome (genetic)
Inherited neuronal ceroid lipofuscinosis
Krabbe disease
Langerhans’-cell histiocytosis
Lesch-Nyhan disease
Leukocyte adhesion deficiency
Osteoporosis (genetic)

Immunodeficiencies

Adenosine deaminase deficiency
(ADA or SCID-ADA)
Severe combined immunodeficiency (SCIDs)
Wiskott-Aldrich syndrome
X-linked lymphoproliferative disease (XLP)

Autologous cells may not be suitable treatment for all inherited genetic conditions. As in any transplant therapy, therapeutic success depends upon many factors beyond the adult stem cells themselves including patient condition, type of disease, recipient-donor relationship and matching and other factors.

The only stem cell-based medical therapies that are currently approved by the FDA and generally available rely on adult stem cells.¹⁷ There are over 700 clinical trials currently underway in the U.S. alone solely focusing on regenerative therapies using adult stem cells.

Click here to view all the current U.S. Government Clinical Trials going on in the area of adult stem cell therapies – US Government Clinical Trials – Clinical Trials on Adult Stem Cells

Adult Stem Cells – Body Illustration

See below an illustration of the many potential therapies using adult stem cells.¹⁸

Assure Immune

1. Understanding Stem Cells National Academies: An overview of the Sciences and Issues for the National Academies, pge 3 - www.nationalacademies.org/stemcells .2. Stem Cell Basics: Introduction . In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2006 Available at http://stemcells.nih.gov/info/basics/basics1 3. Stem Cells and the Future of Regenerative Medicine page 41Copyright 2002 by the National Academy Press by Committee on he Biological and Biomedical Applications of Stem Cell Research, Board on Life Sciences, National Research Council, Board on Neuroscience and Behavioral Health, Institute of Medicine 4. Stem Cell Basics: What are adult stem cells? . In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2006, Available at http://stemcells.nih.gov/info/basics/basics4 5. NIH or Understanding Stem Cells National Acadamies: An overview of the Sciences and Issues for the National Academies, pge 3 - www.nationalacademies.org/stemcells . 6. National Institutes of Health. Stem Cell Information. Available at http://stemcells.nih.gov/info/scireport/execSum.asp 7. International Society for Stem Cell Research. Stem Cell Primer, Page 2 : Available online at http://www.isscr.org/public/ISSCRstemCellPrimer.pdf 8. National Institutes of Health. Stem Cell Information. Available at http://stemcells.nih.gov/info/scireport/execSum.asp 9. Stem Cells and the Future of Regenerative Medicine page 41Copyright 2002 by the National Academy Press by Committee on he Biological and Biomedical Applications of Stem Cell Research, Board on Life Sciences, National Research Council, Board on Neuroscience and Behavioral Health, Institute of Medicine 10. New York Blood Center's National Cord Blood Program: Cord Blood Program Overview: Available online at http://www.nationalcordbloodprogram.org 11. US Census Data Report of total population divided by # of cord blood units being stored in public banks. 50,000.12. National Bone Marrow Program: Life after Transplant section: Available online at http://www.marrow.org/PATIENT/Plan_Life_after_Tx/Managing_Long-Term_Effects_of_/Graft-Versus-Host_Disease/index.html 13. National Marrow Donor Program, Facts & Figures, Page 3: Available online at http://www.marrow.org/NEWS/MEDIA/Facts_and_Figures/facts_figures.pdf . 14. International Society for Stem Cell Research. Stem Cell Primer, Page 2 : Available online at http://www.isscr.org/public/Adult_SC.pdf. 15. In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2007, Available at http://stemcells.nih.gov/info/scireport/2001report 16. Robin R. Young, CFA, Robin Young Consulting Group Inc. and RRY Publications LLC, Stem Cell Analysis and Market Forecasts 2006-2016 17. Stem Cells and the Future of Regenerative Medicine page 41Copyright 2002 by the National Academy Press by Committee on he Biological and Biomedical Applications of Stem Cell Research, Board on Life Sciences, National Research Council, Board on Neuroscience and Behavioral Health, Institute of Medicine, Page 41. 18. Front Matter . In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2006 [cited Wednesday, December 12, 2007] Available at http://stemcells.nih.gov/info/scireport/front

What are the Benefits?

Over 6,000 patients were treated in the U.S. alone with stem cells in 2006. The potential of adult stem cells to impact medicine in this respect is enormous.16

Acute lymphocytic leukemia (ALL)

Acute myelogenous leukemia (AML)

Chronic myelocytic leukemia (CML)

Myelodysplastic syndrome (MDS)

Liposarcoma

Non-Hodgkin’s lymphoma

Yolk sac sarcoma

Amegakaryocytic thrombocytopenia (AMT)

Aplastic anemia

Blackfan-Diamond anemia

Congenital cytopenia

Fanconi’s anemia (genetic)

Kostmann’s syndrome (genetic)

Sickle cell anemia

Adrenoleukodystrophy

Bare-lymphocyte syndrome

Dyskeratosis congenita

Familial erythrophagocytic

lymphohistiocytosis

Gaucher disease

Gunter disease

Adenosine deaminase deficiency (ADA or SCID-ADA)

Severe combined immunodeficiency (SCIDs)

Wiskott-Aldrich syndrome

X-linked lymphoproliferative disease (XLP)

Adult Stem Cells – Body Illustration

See below an illustration of the many potential therapies using adult stem cells.18

Over 6,000 patients were treated in the U.S. alone with stem cells in 2006. The potential of adult stem cells to impact medicine in this respect is enormous.¹⁶

Adenosine deaminase deficiency
(ADA or SCID-ADA)

See below an illustration of the many potential therapies using adult stem cells.¹⁸